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Laboratory Department

The Laboratory Department of the fourth hospital of Hebei Medical University was founded in 1955. In recent decades, the Laboratory Department has developed continuously, rapidly and healthily. With the introduction of new testing technology and the application of laboratory automation and information management methods, the working efficiency, service and scientific research ability of the Department have been continuously improved. In 2014, Department integration, under the leadership of the Department Director, formed a characteristic management mode with lean management as a tool, department culture as a starting point, and ISO15189 as a program. The development of the Department began to take a fast track. In 2015, the Department was awarded as "provincial key clinical laboratory medicine specialty of Hebei Province". In the same year, according to cnas-cl02:2012 "accreditation criteria for quality and ability of medical laboratories" (iso15189:2012, The technical requirements of IDT) have established a complete quality management system. In December 2016, the inspection department took the lead in the province to pass the expert review organized by the national conformity assessment and Accreditation Commission and obtain the ISO15189 accreditation certificate, and then passed the Supervision Review and re review in February 2018 and January 2019 respectively. In just a few years, the comprehensive strength of the laboratory has been in the forefront of clinical laboratory disciplines in the province.

Lab setup

The laboratory covers an area of more than 2000 square meters, under which there are seven professional groups of clinical examination, biochemistry, immunity, microorganism, blood disease, molecular biology and blood collection. It has automatic blood cell analysis line, automatic coagulation analysis line, thrombus elasticity chart, automatic biochemical analysis line, automatic immune analysis line, automatic dry biochemical immune analyzer, automatic nucleic acid extractor, digital PCR instrument, fluorescence quantitative PCR instrument, automatic gene sequencing instrument, automatic immunohistochemistry staining instrument, automatic fluorescence in situ hybridization More than 50 advanced instruments and equipment, such as analyzer, automatic fluorescent immune operation and interpretation system, automatic immunoblotting detection system, automatic blood culture instrument, automatic microbial identification drug sensitivity analyzer, automatic microbial mass spectrometer, automatic medical PCR analyzer, automatic intelligent blood collection system, etc., are built for all sub professional platforms with full-automatic intelligent and integrated laboratory It provides a strong guarantee. More than 400 inspection items are routinely carried out by the laboratory, and more than 95% of them can be issued results on the same day.

Technical team

The Laboratory Department has one director and two deputy directors. At present, there are 58 professional and technical personnel in the Department, including one chief technician, seven deputy chief technicians, two master's supervisors, three doctoral students, 25 master's students, 19 undergraduates, 11 junior college students. The talent structure and ladder team construction are constantly updated.

Discipline development and specialty characteristics

Our college is the former main Committee unit of the Inspection Branch of Hebei Medical Association, the main Committee unit of the cancer molecular medicine special committee of Hebei cancer association and the appointed Main Committee unit of the Inspection Branch of Hebei Medical Association, which undertakes a lot of work of the association, and has made an important contribution to promoting the development of our province's inspection medicine and improving the influence of our province's inspection medicine specialty in the inspection field. The Institute promoted and promoted the accreditation work of ISO15189 medical laboratory in our province by taking multiple measures simultaneously, thus making the quality, ability and management level of laboratory medicine in our province in line with the international standards.

With the characteristics of tumor diagnosis and the comprehensive development of various professional fields, the laboratory provides the most characteristic laboratory services for the majority of patients. The immunology specialty takes the lead in introducing the detection of serological tumor markers in the province, and keeps up with the forefront of professional development, and constantly carries out new projects. At present, 17 tumor markers can be detected, with comprehensive projects and wide coverage, providing valuable data for early diagnosis, dynamic treatment monitoring and prognosis evaluation of tumor patients; in addition, indirect immunofluorescence technology and immunoblotting technology are used to carry out The detection of autoimmune diseases, such as autoimmune liver disease, antinuclear antibody spectrum screening, EB virus antibody spectrum detection, autoimmune diabetes detection, vasculitis antibody detection, has important clinical value for the diagnosis and treatment monitoring of various autoimmune diseases; in the context of precision medicine and individualized medicine, molecular diagnosis is realized by liquid biopsy technology Now, the non-invasive detection of tumor gene map can analyze the key mutations of carcinogenesis in early stage, provide curative effect monitoring, tumor load and prognosis evaluation, and provide strong support for the whole process management of tumor clinical treatment. In hematology specialty, flow cytometry, genetics and immunohistochemical staining are very important auxiliary diagnostic methods for the morphological diagnosis of bone marrow cells. They play an important role in the diagnosis of hematological system diseases, especially in the immunophenotypic analysis of leukemia and lymphoma and the detection of microresidues. The clinical microbiology major focuses on the research of drug resistance mechanism of pathogenic bacteria and the inspection of rare bacteria. It combines traditional microbial inspection technology with new technologies such as microbial mass spectrometry analysis and gene sequencing, which greatly improves the detection rate of pathogenic bacteria and greatly shortens the time of inspection report.

Personnel training and teaching

The Department is responsible for the training and teaching of postgraduates and undergraduates in the school of clinical laboratory diagnostics, Hebei Medical University, and the standardized training base for resident doctors of clinical laboratory specialty approved by the state health and Family Planning Commission, which has trained 28 postgraduates.

Achievements in scientific research

At present, the Department has undertaken one project of National Natural Science Foundation of China (Youth Science Foundation), one project of capacity building and training of professional leaders funded by the government, and many scientific research projects at provincial and ministerial levels. In the past three years, the laboratory has published 8 SCI papers and 23 papers in national core journals, won two first and second prizes of Hebei Medical Science and technology, and one first prize of medical science and technology of Hebei society of traditional Chinese medicine.